Pigeondm2802_228x243_small
Reputation: 593

Why are my psychiatric medications mixing so strangely with alcohol?

First I realize I should not be mixing these drugs at all. I have been attempting to cut down on the alcohol but I haven't always been successful.

I am on Abilify and I have been blacking out a lot. I never blacked out so much in my life than in the past month or so. I've been on other psychiatric medications such as Prozac but they have just caused me to vomit more quickly or pass out.

Does any one have any idea why the Abilify is causing black outs? Or is it causing them at all? I know these medications make the alcohol twice as potent. Is there any reason I would react to alcohol differently on these medications?

I'm really worried too because I think I have been getting into some bad situations while blacked out. Does anyone have any advice on how to deal with a sudden dramatically decreased alcohol tolerance? (Just stopping at one drink is going to be a problem for me because of coexisting issues.)

Thanks for your open minds.

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  • Kendo_20dog_small
    Reputation: 286

    I'm not a doctor, so you should probably check with a real one (and not Dr. Google either--go to an actual, live doctor) to verify this information. Here's what I remember from high school biology class about what happens when alcohol and prescription drugs mix:

    1) If Abilify is processed by your liver, the alcohol might be staying in your system longer without being broken down. When you keep drinking at a steady rate throughout the night, you might keep getting more and more drunk because each shot takes longer to leave your system.

    2) Many antidepressants are synthetic versions of the same feel-good chemicals you get when you drink (the names I remember are serotonin and dopamine, but there are more). It's a complex and delicate system, which is why you probably had to go through a long process of finding the right medication and dosage for you. Pouring a bunch of alcohol on top of those carefully balanced chemicals can have unpredictable results.

    3) The effects of mild drunkenness could be combining with some of Abilify's side effects (drowsiness, maybe?) to produce a severe reaction.

    Tl;dr answer: Stop drinking, and if you can't stop, talk to a doctor about whether another medication would be a better fit for you.

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4 Other Answers

  • Bierce1_small
    Reputation: 640

    "(Just stopping at one drink is going to be a problem for me because of coexisting issues.)"

    Er, you have to face the reality that many drugs DO have a multiplying effect. What are you looking at people to tell you here?

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  • Kermitsex_small
    Reputation: 2421

    Why does it matter if you're blacking out versus throwing up? It doesn't. What does is that you're putting yourself in danger of both nixing the drugs you're taking, and hurting your body further.

    Stop. Yes, l get that drinking on top of it all is due to something or another we aren't privy to, but asking a question like this is a red flag for you; you insist on drinking, you continue to take the pills, and while you're obviously trying to get better, you're deliberately sabotaging yourself. So which is it? Do you want to improve, or do you want to hurt yourself further, not knowing what went down in the process? Trust me, l know a little about this, and you want to care for yourself. And remember what happened the next day.

    Take your meds, and don't drink. Or do, but don't come looking for someone to tell you it's okay to do both -or explain an obvious symptom- if you really want to get better.

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  • Photo_on_2012-01-03_at_17
    Reputation: 628

    Okay, you KNOW you need to stop drinking...

    anyway, in answer to your question regarding specifically Abilify I would hazard to guess that it might be because Abilify is not a typical SSRI. It actually works on a number of different kinds of receptor sites. I can't remember which ones. Look at the wikipedia article if you are interested. It is a partial agonist on dopamine-2 and various 5-HT receptors and others. It is a complex drug, because it doesn't fully block all the dopamine.

    I'm neither a chemist nor a doctor, so I guess you could ask your doctor if you want specifics regarding the chemical make up. My short answer is that it is not a typical SSRI nor a typical antipsychotic, but a newer combo of both, sort of.

    You know this, I'm sure, but you are playing with fire. What you are doing is exceedingly dangerous and you NEED to stop. You don't need to stop at ONE drink. You need to stop at ZERO drinks.

    You might want to tell your p-doc about your alcohol addiction in the mean time. S/he can't help you if s/he doesn't know what s/he is dealing with.

    Abilify and drinking might be even more dangerous than you know, so if your doctor needs to, it might be a good idea to stop the Abilify if you aren't going to stop drinking.

    Seriously, tell your p-doc what is going on. Get some help for the substance abuse. YOU have to decide you want to make the change though. No one can do it for you.

    Be well. I'm sure there are a lot of people who love and care about you out there and they would be heartbroken if anything happened to you!

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  • Ava_small
    Reputation: 539

    It's not what you want to hear but...stop drinking I've been on many head drugs througout the years and rarely have they been good with drinking. You are taking the drugs to feel better. Try them without them hindering especially if you're making poor decisions. Your life will be way worse if you end up in a car accident or get a gnarly STD.
    If after trying the meds straight and you don't like how you're doing talk to your dr. AND don't sugar coat that you drink. Maybe there is a med that would work better with occasional drinking. If you're honest they can work with you. They also need to know of your side effects in order to answer people exactly like you. While the Internet is a great tool self diagnosing can cause problems if you're just treating one aspect. For years different doctors addressed my depression or my add like qualities without thinking my past was important. I finally saw a dr that realized I was bipolar type 2 and I was able to get appropriate medications for different times of the cycle and can manage stuff quite well and at times med free. I don't drink when I'm on the meds because the one that works the best makes me super sick. But I'm much better balanced and happier so it's worth the trade for me.
    But depending on what you're taking the meds for you might be able to supplement if it's light depression, bur again talk to your dr. If they're not comfortable you might get a refferal to bastyr or some place like that and see if you can work in vitamins fish oil and herbal elements that don't react with your drinking ,
    But if you have a more serious reason for the meds though work out what it is honestly, after all alcohol is a depressant. I know it sounds preachy but figure out where your priorities are and work them out with a dr. If you don't like your dr or feel they are judgmental you can always try a different one. Finding one that understands your problems, you past, your choices and goals for your wellbeing is worth it's weight in gold. You're not going to help yourself to your fullest if you don't trust the person trying to help you get what you want out if your regimen
    Good luck it can be tough to manage but well worth it

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