I've had better success with Okcupid than Lovelab, but I definitely feel you on the lack of response issue. My profile is well written (I write for a living), humorous, and genuine. My pics (professional photo shoot) get raves. Still, my response rate is about 10%. I often wonder if it's because I have a kid, but you're probably right - Seattle passive/aggressiveness stikes again.
As for what I respond to:
1. You've got to have decent pics. At least one in-focus close-up where I can actually see your face.
2. You've got to have some modicum of writing ability and originality. I'm probably more picky in this area than the average girl, but I can't tell you how tiresome it is to read yet another profile that starts with "I'm a laid back guy who loves to travel.."
3. Keep past bitterness out of your profile, or anything that starts with "Please don't be..." A little dark humor is ok, but try to keep it mostly light and positive.
4. Huge bonus points for funny. There is way too little humor on the dating sites.
5. Don't tell me about the 10 sports you play or how you travel every chance you get. It makes it sound like you don't have time for a girlfriend.
6. Don't brag. There's way too many guys on these sites who are full of themselves or sound full of themselves. I'm not suggesting you leave out all your stengths, just balance it out with a touch of self-deprecation.
7. I like it when guys address the reader as "you." For example, "I'd love to take you my favorite coffee shop and share secrets." This kind of thing adds intimacy and a little vulnerability, which is nice if you've just read 10 other profiles that all sounded the same.
Hope this is helpful. Good luck, James.